Kinesin

The kinesin dimer (red) attaches to, and moves along, microtubules (blue and green).
Animation of kinesin "walking" on a microtubule

A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases, a type of enzyme). The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo, such as in axonal transport, and intraflagellar transport. Most kinesins walk towards the plus end of a microtubule, which, in most cells, entails transporting cargo such as protein and membrane components from the center of the cell towards the periphery.[1] This form of transport is known as anterograde transport. In contrast, dyneins are motor proteins that move toward the minus end of a microtubule in retrograde transport.

  1. ^ Berg J, Tymoczko JL, Stryer L (2002). "Kinesin and Dynein Move Along Microtubules". Biochemistry. 5th Edition.

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