List of The Powerpuff Girls characters

The Powerpuff Girls is an American animated television series franchise that takes place in the fictional city of Townsville and stars the titular Powerpuff Girls — Blossom, Bubbles and Buttercup — who appear in the original TV series, as well as the anime adaptation, the 2016 reboot series and the upcoming second reboot series.

Secondary characters include Professor Utonium, the girls' father, who created them in his lab; The Mayor, the goodhearted, but dimwitted mayor of Townsville, who frequently calls the girls via a hotline to ask for help to protect the city; Ms. Bellum, the mayor's secretary, who acts as the voice of reason when he makes decisions; and Ms. Keane, the girls' kindergarten teacher at Pokey Oaks school. The primary villains include Mojo Jojo, a hyper-intelligent, megalomaniacal ape; HIM, a mysterious demonic being; Fuzzy Lumpkins, a Bigfoot-like hillbilly; Princess Morbucks, a wealthy, spoiled girl; the Gangreen Gang, five green-skinned hoodlums; Sedusa, a Gorgon-like seductress; the Amoeba Boys, three dimwitted amoebas, and the Rowdyruff Boys, three male evil versions of the Powerpuff Girls.

Series creator Craig McCracken originally conceived the characters while attending the California Institute of the Arts in 1991. McCracken fleshed-out the premise as a short pilot called The Whoopass Girls in Whoopass Stew. After a name change and character redesigns, a new pilot, called "The Powerpuff Girls: Meat Fuzzy Lumkins", aired on Cartoon Network's World Premiere Toons animation showcase in 1995. High viewer approval ratings convinced the network to approve a full series, which premiered in 1998 and ended in 2005.