List of ambassadors of the United States to the Central African Republic

Ambassador of the United States to the Central African Republic
Seal of the United States Department of State
Incumbent Patricia Mahoney since April 8, 2022
Nominator	The President of the United States
Appointer	The President with Senate advice and consent
Inaugural holder	Alan W. Lukens as Chargé d'affaires ad interim
Formation	August 13, 1960
Website	U.S. Embassy - Bangui

The United States ambassador to the Central African Republic is the ambassador of the United States to the Central African Republic.

Alan W. Lukens (resident at Brazzaville) presented credentials as chargé d'affaires ad interim on August 13, 1960. During Blancke's tenure as non-resident ambassador to the Central African Republic, the United States Embassy in Bangui was established on February 10, 1961, with Lukens as resident chargé d'affaires ad interim. Ambassador Cooke was commissioned to the Central African Empire.