List of state highways in Mississippi

Standard route shields
Highway names
Interstates	Interstate X (I-X)
US Highways	U.S. Route X (US X)
State	Mississippi Highway X (MS X)
System links
Mississippi State Highway System Interstate US State

State highways in Mississippi are maintained by the Mississippi Department of Transportation. The state numbers its highways in a grid-like pattern, much like the U.S. Route numbering scheme. One and two-digit routes are primary highways.

Odd-numbered routes run north–south and start from MS 1, which runs along the Mississippi River, to MS 25, which runs near the Alabama border. In addition to routes 1 through 25, routes 27 through 41 repeat this pattern over the first several routes, still increasing in number from west to east, and routes 43 and higher generally run in the southern part of the state.

Even-numbered routes run east–west; these start from MS 2, which runs near the Tennessee state line, and continue to MS 26, which runs in the southern part of the state. With the exception of MS 28, the next several even routes are aligned over routes 2 through 26 in a similar fashion.