The Louisiana Purchase was the acquisition of the Louisiana territory by the United States from France.
Louisiana Purchase may also refer to:
- Louisiana Purchase (musical), a 1940 musical about Louisiana politics
- Louisiana Purchase (film), a 1941 adaptation of the musical
- Louisiana Purchase, conservatives' name for a deal for Mary Landrieu's support of the Patient Protection and Affordable Care Act
- Louisianna Purchase (drag queen), American drag performer
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