Lymphopoiesis

Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cells (WBCs).^[1] It is more formally known as lymphoid hematopoiesis.

Disruption in lymphopoiesis can lead to a number of lymphoproliferative disorders, such as lymphomas and lymphoid leukemias.

Lymphopoiesis Glossary
• antigen any molecule that can provoke an immune defense
• B cells lymphocytes that ultimately produce antibodies
• bone marrow the center of bones capable of producing all red and white blood cells in the adult
• cortex the outer portion of any organ
• cytoplasm the portion of a cell between the nucleus and the membrane
• differentiation permanent changes to a cell developing over time and with cell division
• granules grains found in many white blood cells, composed of defensive chemicals
• hematopoietic that which gives rise to any blood cell type
• lineage a type of cell and its descendants by division and differentiation
• lymphocytes a special 'lineage' of WBC
• macrophages myeloid descendants (some may be lymphoid) with 'eating' abilities, also cooperate with lymphocytes
• myeloid ancestors of WBCs with granules and also of macrophages
• T Cells "management" lymphocytes for immunity
• (WBC) White Blood Cell in contrast to the much more common Red Blood Cell; responsible for defense
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^ Birbrair, Alexander; Frenette, Paul S. (2016-03-01). "Niche heterogeneity in the bone marrow". Annals of the New York Academy of Sciences. 1370 (1): 82–96. Bibcode:2016NYASA1370...82B. doi:10.1111/nyas.13016. ISSN 1749-6632. PMC 4938003. PMID 27015419.

[1] Birbrair, Alexander; Frenette, Paul S. (2016-03-01). "Niche heterogeneity in the bone marrow". Annals of the New York Academy of Sciences. 1370 (1): 82–96. Bibcode:2016NYASA1370...82B. doi:10.1111/nyas.13016. ISSN 1749-6632. PMC 4938003. PMID 27015419.

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