Mary-Claire King

Mary-Claire King
Mary-Claire King in 2016
Born (1946-02-27) February 27, 1946 (age 78)
NationalityAmerican
Alma materCarleton College
University of California, Berkeley
University of California, San Francisco
Known forBreast cancer gene discovery
Forensic genetics for human rights
AwardsGruber Prize in Genetics (2004)
Heineken Prize (2006)
Weizmann Award (2006)
Pearl Meister Greengard Prize (2010)
Lasker Award (2014)
National Medal of Science (2014, awarded 2016)
Shaw Prize in Medicine (2018)
Scientific career
FieldsHuman genetics
InstitutionsUniversity of Washington, University of California, Berkeley
ThesisProtein polymorphisms in chimpanzee and human evolution (1973)
Doctoral advisorAllan Wilson
WebsiteUW Genome Sciences page
External videos
video icon "Meet Dr. Mary-Claire King, Ground-Breaking Geneticist and Tireless Human Rights Activist", World Science Festival, March 5, 2014

Mary-Claire King (born February 27, 1946)[1] is an American geneticist. She was the first to show that breast cancer can be inherited due to mutations in the gene she called BRCA1. She studies human genetics and is particularly interested in genetic heterogeneity and complex traits.[2] She studies the interaction of genetics and environmental influences and their effects on human conditions such as breast and ovarian cancer, inherited deafness, schizophrenia,[3] HIV, systemic lupus erythematosus and rheumatoid arthritis.[4] She has been the American Cancer Society Professor of the Department of Genome Sciences and of Medical Genetics in the Department of Medicine at the University of Washington since 1995.[5]

Besides known for her accomplishment in identifying breast cancer genes, King is also known for demonstrating that humans and chimpanzees are 99% genetically identical and for applying genomic sequencing to identify victims of human rights abuses. In 1984, in Argentina, she began working in identifying children who had been stolen from their families and adopted illegally under the military dictatorship during the Dirty War (1976–1983). She has received many awards, including the Lasker Award and the National Medal of Science. In 2002, Discover magazine recognized King as one of the 50 most important women in science.[6]

  1. ^ Yount, Lisa (2008). "Mary-Claire King" (PDF). A to Z of women in science and math. New York: Facts On File. pp. 153–156. ISBN 978-0816066957.
  2. ^ "Mary-Claire King Professor of Genome Sciences and of Medicine (Medical Genetics)". UW Genome Sciences. Retrieved 12 February 2019.
  3. ^ Cite error: The named reference Angier was invoked but never defined (see the help page).
  4. ^ Bock, Paula (May 19, 2016). "The plan of all plans: Mary-Claire King and her team explore secrets of DNA". Pacific NW Magazine. Retrieved 19 February 2019.
  5. ^ Cite error: The named reference Washington was invoked but never defined (see the help page).
  6. ^ Svitil, Kathy (13 November 2002). "The 50 Most Important Women in Science". Discover. Retrieved 21 December 2014.

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