McMurry reaction

The McMurry reaction is an organic reaction in which two ketone or aldehyde groups are coupled to form an alkene using a titanium chloride compound such as titanium(III) chloride and a reducing agent. The reaction is named after its co-discoverer, John E. McMurry. The McMurry reaction originally involved the use of a mixture TiCl₃ and LiAlH₄, which produces the active reagents. Related species have been developed involving the combination of TiCl₃ or TiCl₄ with various other reducing agents, including potassium, zinc, and magnesium.^[1][2] This reaction is related to the Pinacol coupling reaction which also proceeds by reductive coupling of carbonyl compounds.