Multiple endocrine neoplasia type 1

Multiple endocrine neoplasia type 1
Other namesMEN-1 syndrome, Wermer's syndrome
Multiple endocrine neoplasia type 1 is inherited in an autosomal dominant manner.
SpecialtyOncology, endocrine surgery Edit this on Wikidata

Multiple endocrine neoplasia type 1 (MEN-1) is one of a group of disorders, the multiple endocrine neoplasias, that affect the endocrine system through development of neoplastic lesions in pituitary, parathyroid gland and pancreas.[1] Individuals suffering from this disorder are prone to developing multiple endocrine and nonendocrine tumors.[2][3] It was first described by Paul Wermer in 1954.[4]

  1. ^ Lemmens I, Van de Ven WJ, Kas K, Zhang CX, Giraud S, Wautot V, et al. (July 1997). "Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1". Human Molecular Genetics. 6 (7): 1177–1183. doi:10.1093/hmg/6.7.1177. PMID 9215690.
  2. ^ Duro T, Gonzales KL (2023-01-01). "Adrenal Liposarcoma: A Novel Presentation of Multiple Endocrine Neoplasia Type 1". AACE Clinical Case Reports. 9 (1): 10–12. doi:10.1016/j.aace.2022.11.003. PMC 9837086. PMID 36654999.
  3. ^ Thakker RV, Newey PJ, Walls GV, Bilezikian J, Dralle H, Ebeling PR, et al. (September 2012). "Clinical practice guidelines for multiple endocrine neoplasia type 1 (MEN1)". The Journal of Clinical Endocrinology and Metabolism. 97 (9): 2990–3011. doi:10.1210/jc.2012-1230. PMID 22723327. S2CID 40362497.
  4. ^ Wermer P (March 1954). "Genetic aspects of adenomatosis of endocrine glands". The American Journal of Medicine. 16 (3): 363–371. doi:10.1016/0002-9343(54)90353-8. PMID 13138607.

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