Neural fold

Neural fold
Chick embryo of thirty-three hours’ incubation, viewed from the dorsal aspect. 30x. (Neural fold labeled at center left, third from the bottom.)
Details
Carnegie stage	9
Precursor	Neural plate
Gives rise to	Neural tube
Identifiers
Latin	plica neuralis
TE	fold_by_E5.13.1.0.1.0.2 E5.13.1.0.1.0.2
Anatomical terminology [edit on Wikidata]

The neural fold is a structure that arises during neurulation in the embryonic development of both birds and mammals among other organisms.^[1][2] This structure is associated with primary neurulation, meaning that it forms by the coming together of tissue layers, rather than a clustering, and subsequent hollowing out, of individual cells (known as secondary neurulation). In humans, the neural folds are responsible for the formation of the anterior end of the neural tube. The neural folds are derived from the neural plate, a preliminary structure consisting of elongated ectoderm cells. The folds give rise to neural crest cells, as well as bringing about the formation of the neural tube.^[1][3]