Neurolysis

Neurolysis is the application of physical or chemical agents to a nerve in order to cause a temporary degeneration of targeted nerve fibers. When the nerve fibers degenerate, an interruption in the transmission of nerve signals occurs. In the medical field, neurolysis is commonly used to alleviate pain, such as in people with various forms of cancer, chronic osteoarthritis or spasticity.[1][2]

Different types of neurolysis include celiac plexus neurolysis, endoscopic ultrasound guided neurolysis, and lumbar sympathetic neurolysis.[1] Chemodenervation and nerve blocks are other forms of neurolysis.[1]

Neurotomy may refer to the application of heat (as in radiofrequency nerve lesioning), chemical ablation, or freezing of sensory nerves with the intent of a longer term (months or years) ablation or partial denervation of one or more peripheral nerves, usually to relieve chronic pain.[1][3][4]

  1. ^ a b c d Ben Aziz M, Cascella M (6 October 2024). "Neurolytic procedures". StatPearls, US National Library of Medicine. Retrieved 11 February 2025.
  2. ^ Cite error: The named reference tay was invoked but never defined (see the help page).
  3. ^ "Radiofrequency neurotomy". Mayo Clinic. 6 April 2024. Retrieved 5 September 2024.
  4. ^ "Radiofrequency ablation for pain management". Cleveland Clinic. 14 March 2022. Retrieved 5 September 2024.

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