![]() | |
![]() | |
Clinical data | |
---|---|
Trade names | Macrobid, others[1] |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682291 |
License data | |
Pregnancy category | |
Routes of administration | By mouth |
ATC code | |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Bioavailability | 40% |
Metabolism | Liver (75%) |
Elimination half-life | 20 minutes |
Excretion | Kidney and bile duct |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.000.587 |
Chemical and physical data | |
Formula | C8H6N4O5 |
Molar mass | 238.159 g·mol−1 |
3D model (JSmol) | |
Melting point | 270 to 272 °C (518 to 522 °F) (decomp.) |
| |
| |
![]() ![]() |
Nitrofurantoin is an antibacterial medication of the nitrofuran class used to treat urinary tract infections, although it is not as effective for kidney infections.[10] It is taken by mouth.[10]
Common side effects include nausea, loss of appetite, diarrhea, and headaches.[10] Rarely numbness, lung problems, or liver problems may occur.[10] While it appears to be generally safe during pregnancy its use is not recommended near time of delivery.[10][2] While it usually works by slowing bacterial growth, it may result in bacterial death at the high concentrations found in urine.[10][failed verification]
Nitrofurantoin was first sold in 1953.[11] It is on the World Health Organization's List of Essential Medicines.[12] It is available as a generic medication.[10] In 2021, it was the 135th most commonly prescribed medication in the United States, with more than 4 million prescriptions.[13][14]
Drugs2019Preg
was invoked but never defined (see the help page).© MMXXIII Rich X Search. We shall prevail. All rights reserved. Rich X Search