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Addiction liability | High |
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CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.161.803 |
Chemical and physical data | |
Formula | C16H19NO4 |
Molar mass | 289.331 g·mol−1 |
3D model (JSmol) | |
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Norcocaine is a minor metabolite of cocaine. It is the only confirmed pharmacologically active metabolite of cocaine,[1] although salicylmethylecgonine is also speculated to be an active metabolite. The local anesthetic potential of norcocaine has been shown to be higher than that of cocaine,[2][3] however cocaine continues to be more widely used. Norcocaine used for research purposes is typically synthesized from cocaine. Several methods for the synthesis have been described.[4][5]
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