Paul Ehrlich | |
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Born | 14 March 1854 |
Died | 20 August 1915 | (aged 61)
Citizenship | German |
Known for | Chemotherapy Immunology Basophil Magic bullet Mast cell Receptor theory Side-chain theory Ehrlich's reagent |
Spouse | Hedwig Pinkus (1864–1948) (m. 1883; 2 children) |
Children | Stephanie and Marianne |
Awards | Nobel Prize in Physiology or Medicine (1908) Cameron Prize of the University of Edinburgh (1914) |
Scientific career | |
Fields | Immunology |
Thesis | Beiträge zur Theorie und Praxis der histologischen Färbung (1878) |
Notable students | Hans Schlossberger |
Signature | |
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Paul Ehrlich (German: [ˈpaʊl ˈʔeːɐ̯lɪç] ; 14 March 1854 – 20 August 1915) was a Nobel Prize-winning German physician and scientist who worked in the fields of hematology, immunology and antimicrobial chemotherapy. Among his foremost achievements were finding a cure for syphilis in 1909 and inventing the precursor technique to Gram staining bacteria. The methods he developed for staining tissue made it possible to distinguish between different types of blood cells, which led to the ability to diagnose numerous blood diseases.
His laboratory discovered arsphenamine (Salvarsan), the first antibiotic and first effective medicinal treatment for syphilis, thereby initiating and also naming the concept of chemotherapy. Ehrlich popularised the concept of a magic bullet. He also made a decisive contribution to the development of an antiserum to combat diphtheria and conceived a method for standardising therapeutic serums.[1]
In 1908, he received the Nobel Prize in Physiology or Medicine for his contributions to immunology.[2] He was the founder and first director of what is now known as the Paul Ehrlich Institute, a German research institution and medical regulatory body that is the nation's federal institute for vaccines and biomedicines. A genus of Rickettsiales bacteria, Ehrlichia, is named after him.[3]
Ehrlich has been called "father of immunology".[4][5]
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