Back نقل الصفائح الدموية Arabic Transfusió de plaquetes Catalan Transfusión de plaquetas Spanish Transfusion de plaquettes French עירוי טסיות דם HE ପ୍ଲାଟେଲେଟ ଟ୍ରାନ୍ସଫ୍ୟୁଜନ OR Truyền tiểu cầu Vietnamese

Platelet transfusion

Platelet transfusion
A bag of platelets
Clinical data
Other namesPlatelet concentrate, platelet component
ATC code
Identifiers
ChemSpider
  • none

Platelet transfusion, also known as platelet concentrate, is used to prevent or treat bleeding in people with either a low platelet count or poor platelet function.[1] Often this occurs in people receiving cancer chemotherapy.[1] Preventive transfusion is often done in those with platelet levels of less than 10 x 109/L.[2] In those who are bleeding transfusion is usually carried out at less than 50 x 109/L.[2] Blood group matching (ABO, RhD) is typically recommended before platelets are given.[2] Unmatched platelets, however, are often used due to the unavailability of matched platelets.[3] They are given by injection into a vein.[4]

Side effects can include allergic reactions such as anaphylaxis, infection, and lung injury.[2] Bacterial infections are relatively more common with platelets as they are stored at warmer temperatures.[2] Platelets can be produced either from whole blood or by apheresis.[1] They keep for up to five to seven days.[1]

Platelet transfusions came into medical use in the 1950s and 1960s.[1][5] It is on the World Health Organization's List of Essential Medicines.[6][7] Some versions of platelets have had the white blood cells partially removed or been gamma irradiated which have specific benefits for certain populations.[8]

  1. ^ a b c d e Fisk JM, Pisciotto PT, Snyder EL, Perrota PL (2007). "Platelets and related products". In Hillyer CD, Silberstein LE, Ness PM, Anderson KC, Roback JD (eds.). Blood Banking and Transfusion Medicine: Basic Principles & Practice. Elsevier Health Sciences. pp. 308–310. ISBN 978-0443069819. Archived from the original on 2017-01-12.
  2. ^ a b c d e Connell NT (December 2016). "Transfusion Medicine". Primary Care. 43 (4): 651–659. doi:10.1016/j.pop.2016.07.004. PMID 27866583.
  3. ^ Josephson CD, Castillejo MI, Grima K, Hillyer CD (February 2010). "ABO-mismatched platelet transfusions: strategies to mitigate patient exposure to naturally occurring hemolytic antibodies". Transfusion and Apheresis Science. 42 (1): 83–88. doi:10.1016/j.transci.2009.10.013. PMID 20034854.
  4. ^ Flagg C (2015). "Intravenous Therapy". In Linton AD (ed.). Introduction to Medical-Surgical Nursing. Elsevier Health Sciences. p. 287. ISBN 978-1455776412. Archived from the original on 2017-01-12.
  5. ^ Das PC, Smit-Sibinga CT, Halie MR (2012). Supportive therapy in haematology. Springer Science & Business Media. p. 190. ISBN 978-1461325772. Archived from the original on 2017-01-10.
  6. ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  7. ^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.
  8. ^ Hillyer CD, Silberstein LE, Ness PM, Anderson KC, Roback JD, eds. (2007). Blood Banking and Transfusion clinical Basic Principles & Practice. Elsevier Health Sciences. p. 320. ISBN 978-0443069819. Archived from the original on 2017-01-12.

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