Polyene

In organic chemistry, polyenes are polyunsaturated organic compounds that contain multiple carbon–carbon double bonds (C=C).^[1]^[2] Some sources consider dienes to be polyenes,^[3] whereas others require polyenes to contain at least three carbon–carbon double bonds.^[4]

Conjugated polyenes contain a conjugated system of alternating single and double carbon–carbon bonds, with characteristic optical properties.

The following polyenes are used as antimycotics for humans: amphotericin B, nystatin, candicidin, pimaricin, methyl partricin, and trichomycin.^[5]

^ Sharp, DWA, ed. (1990). The Penguin Dictionary of Chemistry (2nd ed.). London, England ; New York, N.Y., USA: Penguin Books. p. 320. ISBN 9780140512328.
^ Oxford Dictionary of English (2nd, rev ed.). Oxford ; New York: Oxford University Press. 2005. p. 1364. ISBN 9780198610571.
^ Oxford Dictionary of Biochemistry and Molecular Biology (1st, rev ed.). Oxford: Oxford University Press. 1997. p. 520. ISBN 9780198506737.
^ Benet‐Buchholz, Jordi; Boese, Roland; Haumann, Thomas; Traetteberg, Marit (15 March 1997). "Structural Chemistry of Dienes and Polyenes". The Chemistry of Dienes and Polyenes. pp. 25–65. doi:10.1002/0470857218.ch2.
^ Zotchev, Sergey B. (2003). "Polyene macrolide antibiotics and their applications in human therapy". Current Medicinal Chemistry. 10 (3): 211–223. doi:10.2174/0929867033368448. PMID 12570708.