Post-exertional malaise | |
---|---|
Other names | Post-exertional symptom exacerbation (PESE) Postexertional malaise (PEM) Post-exertional neuroimmune exhaustion (PENE) |
![]() | |
Chart of physical, cognitive, and emotional activities that may trigger PEM | |
Symptoms | Worsening of symptoms after ordinary activity |
Causes | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Long COVID[citation needed] |
Treatment | Symptomatic |
Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE)[1] or post-exertional neuroimmune exhaustion (PENE),[2] is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and fibromyalgia.[3][1] PEM is often severe enough to be disabling, and is triggered by ordinary activities that healthy people tolerate. Typically, it begins 12–48 hours after the activity that triggers it, and lasts for days, but this is highly variable and may persist much longer.[4][5][6] Management of PEM is symptom-based, and patients are recommended to pace their activities to avoid triggering PEM.
© MMXXIII Rich X Search. We shall prevail. All rights reserved. Rich X Search