Potassium-sparing diuretics or antikaliuretics[1] refer to drugs that cause diuresis without causing potassium loss in the urine.[2] They are typically used as an adjunct in management of hypertension, cirrhosis, and congestive heart failure.[3] The steroidal aldosterone antagonists can also be used for treatment of primary hyperaldosteronism. Spironolactone, a steroidal aldosterone antagonist, is also used in management of female hirsutism and acne from PCOS or other causes.[4][5]
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