President's Emergency Plan for AIDS Relief

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The United States President's Emergency Plan For AIDS Relief (PEPFAR) is the global health funding by the United States to address the global HIV/AIDS epidemic and help save the lives of those suffering from the disease. As of 2023, PEPFAR has saved over 25 million lives,[1][2] primarily in sub-Saharan Africa.[3][4]

Launched by U.S. President George W. Bush in 2003, as of August 2024, PEPFAR has provided cumulative funding of $120 billion for HIV/AIDS treatment, prevention, and research since its inception, making it the largest commitment by any nation focused on a single disease in history.[3] PEPFAR is implemented by a combination of U.S. government agencies in over 50 countries and overseen by the Global AIDS Coordinator at the United States Department of State.[5]

The PEPFAR program has in recent years been criticized by members of the Republican Party who have sought to block its re-authorization. Republicans alleged that the program promoted abortion.[6][7] In 2025, the second administration of President Donald Trump put USAID on a 90-day freeze which involved putting PEPFAR on halt and taking its computer systems offline.[7]

On January 28, 2025 the Trump administration granted a waiver for essential medicines and medical services, temporarily restoring a global HIV treatment program that they had suspended the previous week.[8] U.S. Secretary of State Marco Rubio announced the waiver, which appeared to permit the distribution of HIV medications.[9]

However, it remained unclear whether the exemption covered preventive drugs or additional services provided through PEPFAR. Senator Bill Cassidy (R-Louisiana), who is a medical doctor, posted on February 4, 2025 that money for PEPFAR does not seem to be flowing.[10] Through mid-April 2025, the country of Zambia had not had its PEPFAR program restarted.[11]

  1. ^ "PEPFAR - HIV.gov". March 2, 2023. Retrieved July 2, 2023.
  2. ^ Beauchamp, Zack (July 28, 2023). "Republicans are threatening to sabotage George W. Bush's greatest accomplishment". Vox. Retrieved July 29, 2023.
  3. ^ a b "The U.S. President's Emergency Plan for AIDS Relief (PEPFAR)". The Henry J. Kaiser Family Foundation. May 27, 2020. Retrieved March 26, 2025.
  4. ^ Fauci, Anthony S.; Eisinger, Robert W. (January 25, 2018). "PEPFAR — 15 Years and Counting the Lives Saved". New England Journal of Medicine. 378 (4): 314–316. doi:10.1056/NEJMp1714773. ISSN 0028-4793. PMID 29365298.
  5. ^ "About Us". www.pepfar.gov. Retrieved March 26, 2019.
  6. ^ Weixel, Nathaniel (March 1, 2024). "US AIDS relief program gets one-year extension in spending bill". The Hill. Retrieved February 5, 2025.
  7. ^ a b Mandavilli, Apoorva (January 27, 2025). "Trump Administration Halts H.I.V. Drug Distribution in Poor Countries". The New York Times. ISSN 0362-4331. Retrieved January 28, 2025.
  8. ^ Mandavilli, Apoorva (January 29, 2025). "State Department Permits Distribution of H.I.V. Medications to Resume — for Now". The New York Times. ISSN 0362-4331. Retrieved January 31, 2025.
  9. ^ "Rubio's emergency humanitarian waiver was the right thing to do". George W. Bush Presidential Center. January 29, 2025. Retrieved January 31, 2025.
  10. ^ “Crucial aid sits in warehouses worldwide as USAID employees are told to stop working,” Suzy Khimm, Feb 4, 2025.
  11. ^ Gabrielle Emanuel; Rebecca Davis; Ben de la Cruz, photography (April 14, 2025). "Haunted by hopelessness: 12 Zambians share their stories as HIV drugs run out". NPR.

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