Primate basal ganglia

Diagram of the main components of the basal ganglia and their interconnections.
GPe = External globus pallidus
GPi = Internal globus pallidus
STN = Subthalamic nucleus
SNpr = Pars reticulata
SNpc = Pars compacta
Glutamatergic pathways are red, dopaminergic pathways are magenta and GABAergic pathways are blue.

The basal ganglia form a major brain system in all vertebrates, but in primates (including humans) there are special differentiating features. The basal ganglia include the striatum, pallidus, substantia nigra and subthalamic nucleus. In primates the pallidus is divided into an external and internal globus pallidus, the external globus pallidus is present in other mammals but not the internal globus pallidus. Also in primates, the dorsal striatum is divided by a large nerve tract called the internal capsule into two masses named the caudate nucleus and the putamen. These differences contribute to a complex circuitry of connections between the striatum and cortex that is specific to primates, reflecting different functions in primate cortical areas.


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