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Prophase

Prophase is the first step of cell division in mitosis. As it occurs after G2 of interphase, DNA has been already replicated when prophase begins.[1]
Fluorescence microscope image of two mouse cell nuclei in prophase (scale bar is 5 μm).[2]

Prophase (from Ancient Greek προ- (pro-) 'before', and φάσις (phásis) 'appearance') is the first stage of cell division in both mitosis and meiosis. Beginning after interphase, DNA has already been replicated when the cell enters prophase. The main occurrences in prophase are the condensation of the chromatin reticulum and the disappearance of the nucleolus.[3]

  1. ^ Nussbaum RL, McInnes RR, Huntington F (2016). Thompson & Thompson Genetics in Medicine. Philadelphia: Elsevier. pp. 12–20. ISBN 9781437706963.
  2. ^ Schermelleh L, Carlton PM, Haase S, Shao L, Winoto L, Kner P, et al. (June 2008). "Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy". Science. 320 (5881): 1332–36. Bibcode:2008Sci...320.1332S. doi:10.1126/science.1156947. PMC 2916659. PMID 18535242.
  3. ^ Cite error: The named reference :2 was invoked but never defined (see the help page).

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