Prostacyclin

Prostacyclin

Clinical data
Trade names	Flolan, Veletri
AHFS/Drugs.com	Monograph
License data	US DailyMed: Epoprostenol_sodium
Pregnancy category	AU: B1
ATC code	B01AC09 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) US: ℞-only
Pharmacokinetic data
Elimination half-life	42 seconds
Identifiers
IUPAC name (Z)-5-[(4R,5R)-5-Hydroxy-4-((S,E)-3-hydroxyoct-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid
CAS Number	35121-78-9 Y
PubChem CID	5282411
IUPHAR/BPS	1915
DrugBank	DB01240 N
ChemSpider	102770 N
UNII	DCR9Z582X0
KEGG	D00106 as salt: D01337
ChEMBL	ChEMBL1139 N
CompTox Dashboard (EPA)	DTXSID5022988
Chemical and physical data
Formula	C20H32O5
Molar mass	352.471 g·mol−1
3D model (JSmol)	Interactive image
SMILES OC(=O)CCC\C=C1\C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]2O1
InChI InChI=1S/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24)/b11-10+,15-8-/t14-,16+,17+,18+,19-/m0/s1 N Key:KAQKFAOMNZTLHT-OZUDYXHBSA-N N
NY (what is this?)  (verify)

Prostacyclin (also called prostaglandin I₂ or PGI₂) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator.

When used as a drug, it is also known as epoprostenol.^[1] The terms are sometimes used interchangeably.^[2]