Protein pigeon homolog

GSAP
Identifiers
Aliases	GSAP, PION, Protein pigeon homolog, gamma-secretase activating protein
External IDs	OMIM: 613552; MGI: 2442259; HomoloGene: 45504; GeneCards: GSAP; OMA:GSAP - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	77,416,349 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	21,520,130 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; right uterine tube; ; monocyte; ; spleen; ; right lung; ; epithelium of nasopharynx; ; visceral pleura; ; right lobe of thyroid gland; ; secondary oocyte; ; upper lobe of left lung;
	Top expressed in
	lumbar spinal ganglion; ; granulocyte; ; right lung; ; spermatid; ; right lung lobe; ; right kidney; ; Rostral migratory stream; ; left lobe of liver; ; tibiofemoral joint; ; proximal tubule;
	More reference expression data
	n/a
Gene ontology
Molecular function	amyloid-beta binding; protein binding;
Cellular component	trans-Golgi network; Golgi apparatus;
Biological process	regulation of proteolysis; positive regulation of amyloid-beta formation;
	Sources:Amigo / QuickGO
Orthologs
	54103
	212167
	ENSG00000186088
	ENSMUSG00000039934
	A4D1B5
	Q3TCV3
NM_017439; NM_001350896; NM_001350897; NM_001350898; NM_001350899;
	NM_001350900; NM_001350901
	NM_175437; NM_001359876; NM_001359877
NP_059135; NP_001337825; NP_001337826; NP_001337827; NP_001337828;
	NP_001337829; NP_001337830
	NP_780646; NP_001346805; NP_001346806
	Wikidata
View/Edit Human	View/Edit Mouse

Protein pigeon homolog also known as gamma-secretase activating protein (GSAP) is a protein that in humans is encoded by the PION gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186088 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000039934 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: pigeon homolog (Drosophila)".