Psoriatic arthritis

Psoriatic arthritis
Other namesArthritis psoriatica, arthropathic psoriasis, psoriatic arthropathy, psoriatic disease.[1]
Severe psoriatic arthritis of both feet and ankles. There is also damage to the nails.
SpecialtyRheumatology

Psoriatic arthritis (PsA) is a long-term inflammatory arthritis that may occur in some people affected by the autoimmune disease psoriasis.[2][3] The classic features of psoriatic arthritis include dactylitis (sausage-like swelling of the fingers), skin lesions, and nail lesions.[4] Lesions of the nails may include small depressions in the nail (pitting), thickening of the nails, and detachment of the nail from the nailbed.[4] Skin lesions consistent with psoriasis (e.g., red, scaly, and itchy plaques) frequently occur before the onset of psoriatic arthritis but psoriatic arthritis can precede the rash in 15% of affected individuals.[4] It is classified as a type of seronegative spondyloarthropathy.

Genetics are thought to be strongly involved in the development of psoriatic arthritis.[4] Obesity and certain forms of psoriasis are thought to increase the risk.[4]

Psoriatic arthritis affects up to 30% of people with psoriasis. It occurs in both children and adults.[4] Some people with PsA never get psoriasis.[5]

The condition is less common in people of Asian or African descent. It affects men and women equally.[4]

  1. ^ Rossi D, Roccatello D, Rubini E, Sciascia S, Modena V (2024). "Psoriatic Arthritis". In Roccatello D, Emmi L (eds.). Connective Tissue Disease: A Comprehensive Guide - Volume 2. Springer Nature. pp. 27–44. ISBN 978-3-031-60855-1.
  2. ^ Freedberg, Irwin M., Fitzpatrick, Thomas B. (2003). Fitzpatrick's dermatology in general medicine (6th ed.). New York: McGraw-Hill. pp. 427–436. ISBN 978-0-07-138076-8.
  3. ^ James, William, Berger, Timothy, Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. p. 194. ISBN 978-0-7216-2921-6.
  4. ^ a b c d e f g Ritchlin CT, Colbert RA, Gladman DD (March 2017). "Psoriatic Arthritis". New England Journal of Medicine (Review). 376 (10): 957–70. doi:10.1056/NEJMra1505557. PMID 28273019. S2CID 43867408.
  5. ^ "Are You at Risk for Psoriatic Arthritis?". www.psoriasis.org.

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