RNA polymerase V

RNA polymerase V (Pol V), previously known as RNA polymerase IVb, is a multisubunit plant specific RNA polymerase. It is required for normal function and biogenesis of small interfering RNA (siRNA). Together with RNA polymerase IV (Pol IV), Pol V is involved in an siRNA-dependent epigenetic pathway known as RNA-directed DNA methylation (RdDM), which establishes and maintains heterochromatic silencing in plants.[1]

  1. ^ Wierzbicki, A; Haag, J; Pikaard, CS (2008). "Noncoding transcription by RNA Polymerase Pol IVb/Pol V mediates transcriptional silencing of overlapping and adjacent genes". Cell. 135 (4): 635–648. doi:10.1016/j.cell.2008.09.035. PMC 2602798. PMID 19013275.

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