Romanowsky stain

Romanowsky staining is a prototypical staining technique that was the forerunner of several distinct but similar stains widely used in hematology (the study of blood) and cytopathology (the study of diseased cells). Romanowsky-type stains are used to differentiate cells for microscopic examination in pathological specimens, especially blood and bone marrow films,^[1] and to detect parasites such as malaria within the blood.^[2]^[3]^[4]^[5]

The staining technique is named after the Russian physician Dmitri Leonidovich Romanowsky (1861–1921), who was one of the first to recognize its potential for use as a blood stain.^[6]

Stains that are related to or derived from the Romanowsky-type stains include Giemsa, Jenner, Wright, Field, May–Grünwald, Pappenheim and Leishman stains. They differ in protocols and additives and their names are often confused with one another in practice.

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[Marshall,_1978-4] Cite error: The named reference Marshall, 1978 was invoked but never defined (see the help page).

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[Bezrukov,_2017-6] Cite error: The named reference Bezrukov, 2017 was invoked but never defined (see the help page).

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