Back رومولوس وريموس وكاليسي Arabic Romulus, Remus, asin Khaleesi BCL Romulus, Remus i Khaleesi Catalan Rómulo, Remo y Khaleesi Spanish رمولوس، رموس و کالیسی Persian Romulus, Remus ja Khaleesi Finnish Romulus, Remus et Khaleesi French Ромул, Рем и Кхалиси Russian Colossal Biosciences jättevarg-projekt Swedish โรมุลุส, แรมุส, และคาลีซี Thai
 | A request that this article title be changed to Colossal Biosciences Dire Wolf Project is under discussion. Please do not move this article until the discussion is closed. |
| Species | Gray wolves (Canis lupus) |
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| Born |
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| Known for | Purportedly being the first de-extincted dire wolves (Aenocyon dirus) |
| Named after |
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| https://colossal.com/direwolf/ | |
Romulus, Remus, and Khaleesi are genetically modified gray wolves (Canis lupus) created by Colossal Biosciences Inc. with the goal of replicating the phenotype of the extinct dire wolf (Aenocyon dirus). Romulus and Remus were born on October 1, 2024; Colossal claims that the two males represent the first living examples of the species since its extinction approximately 10,000 years ago. Khaleesi, a female, was born later, on January 30, 2025. Due to significant genetic differences from Aenocyon, the dire wolf genus, Romulus, Remus, and Khaleesi are in fact genetically engineered gray wolves.
Scientists rewrote 14 key genes in gray wolf EPC cells to express 20 dire wolf traits meaning that "no ancient dire wolf DNA was actually spliced into the grey wolf's genome."[1] The public announcement of their birth in April 2025 was subject to significant public attention.[2]
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