Back لقاح الفيروس العجلي Arabic Rotavirusimpfstoff German Εμβόλιο ιού ρότα Greek Vacuna contra el rotavirus Spanish Rotavirusrokote Finnish Rotavirus#Vaccins French Allurar rigakafin Rotavirus Hausa Rotavírus elleni védőoltás Hungarian Ռոտավիրուսի պատվաստանյութ Armenian Vaksin Rotavirus ID

Rotavirus vaccine

Rotavirus vaccine
Vaccine description
TargetRotavirus
Vaccine typeAttenuated
Clinical data
Trade namesRotarix, Rotateq, others
AHFS/Drugs.comMonograph
MedlinePlusa607024
License data
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
  • none
KEGG
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A rotavirus vaccine is a vaccine used to protect against rotavirus infections, which are the leading cause of severe diarrhea among young children.[6] These vaccines prevent 15–34% of severe diarrhea in the developing world and 37–96% of the risk of death among young children due to severe diarrhea.[6] Immunizing babies decreases rates of rotavirus disease among older people and those who have not been immunized.[7]

The World Health Organization (WHO) recommends that rotavirus vaccine be included in national routine vaccinations programs, especially in areas where the disease is common.[6] This should be done along with promoting breastfeeding, handwashing, clean water, and good sanitation.[6] They are given by mouth and two or three doses are required.[6] The approved vaccines are recommended.[6] This includes their use in people with HIV/AIDS.[6] The vaccines are made with weakened[6] rotavirus.

The currently licensed live oral vaccine first became available in the United States in 2006.[8] They are on the World Health Organization's List of Essential Medicines.[9] The vaccines are available in many countries.[6]

  1. ^ "Rotarix- rotavirus vaccine, live, oral kit; Rotarix- rotavirus vaccine, live, oral solution". DailyMed. 24 January 2024. Archived from the original on 1 December 2023. Retrieved 27 May 2024.
  2. ^ "Rotateq- rotavirus vaccine, live, oral, pentavalent solution". DailyMed. 7 March 2023. Archived from the original on 12 September 2023. Retrieved 27 May 2024.
  3. ^ "Rotarix EPAR". European Medicines Agency (EMA). 21 February 2006. Archived from the original on 1 December 2023. Retrieved 27 May 2024.
  4. ^ "Rotateq". European Medicines Agency (EMA). 27 June 2006. Archived from the original on 2 May 2024. Retrieved 27 May 2024.
  5. ^ "Rotashield EPAR". European Medicines Agency (EMA). 7 June 2001. Archived from the original on 1 October 2022. Retrieved 27 May 2024.
  6. ^ a b c d e f g h i "Rotavirus vaccines. WHO position paper – January 2013". Relevé Épidémiologique Hebdomadaire. 88 (5): 49–64. February 2013. hdl:10665/242024. PMID 23424730.
  7. ^ Patel MM, Steele D, Gentsch JR, Wecker J, Glass RI, Parashar UD (January 2011). "Real-world impact of rotavirus vaccination". The Pediatric Infectious Disease Journal. 30 (1 Suppl): S1 – S5. doi:10.1097/INF.0b013e3181fefa1f. PMID 21183833. S2CID 1893099.
  8. ^ "Rotavirus Vaccine Live Oral". The American Society of Health-System Pharmacists. Archived from the original on 22 December 2015. Retrieved 14 December 2015.
  9. ^ World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.

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