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Rotavirus vaccine

Rotavirus vaccine
Vaccine description
TargetRotavirus
Vaccine typeAttenuated
Clinical data
Trade namesRotarix, Rotateq, others
AHFS/Drugs.comMonograph
MedlinePlusa607024
License data
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
  • none
KEGG
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The rotavirus vaccine is a vaccine used to protect against rotavirus infections, which are the leading cause of severe diarrhea among young children.[6] The vaccines prevent 15–34% of severe diarrhea in the developing world and 37–96% of the risk of death among young children due to severe diarrhea.[6] Immunizing babies decreases rates of disease among older people and those who have not been immunized.[7]

The World Health Organization (WHO) recommends that rotavirus vaccine be included in national routine vaccinations programs, especially in areas where the disease is common.[6] This should be done along with promoting breastfeeding, handwashing, clean water, and good sanitation.[6] It is given by mouth and requires two or three doses.[6] The vaccines are safe.[6] This includes their use in people with HIV/AIDS.[6] The vaccines are made from weakened rotavirus.[6]

The vaccine first became available in the United States in 2006.[8] It is on the World Health Organization's List of Essential Medicines.[9] The vaccine is available in many countries.[6]

  1. ^ "Rotarix- rotavirus vaccine, live, oral kit; Rotarix- rotavirus vaccine, live, oral solution". DailyMed. 24 January 2024. Archived from the original on 1 December 2023. Retrieved 27 May 2024.
  2. ^ "Rotateq- rotavirus vaccine, live, oral, pentavalent solution". DailyMed. 7 March 2023. Archived from the original on 12 September 2023. Retrieved 27 May 2024.
  3. ^ "Rotarix EPAR". European Medicines Agency (EMA). 21 February 2006. Archived from the original on 1 December 2023. Retrieved 27 May 2024.
  4. ^ "Rotateq". European Medicines Agency (EMA). 27 June 2006. Archived from the original on 2 May 2024. Retrieved 27 May 2024.
  5. ^ "Rotashield EPAR". European Medicines Agency (EMA). 7 June 2001. Archived from the original on 1 October 2022. Retrieved 27 May 2024.
  6. ^ a b c d e f g h i "Rotavirus vaccines. WHO position paper – January 2013". Relevé Épidémiologique Hebdomadaire. 88 (5): 49–64. February 2013. hdl:10665/242024. PMID 23424730.
  7. ^ Patel MM, Steele D, Gentsch JR, Wecker J, Glass RI, Parashar UD (January 2011). "Real-world impact of rotavirus vaccination". The Pediatric Infectious Disease Journal. 30 (1 Suppl): S1–S5. doi:10.1097/INF.0b013e3181fefa1f. PMID 21183833. S2CID 1893099.
  8. ^ "Rotavirus Vaccine Live Oral". The American Society of Health-System Pharmacists. Archived from the original on 22 December 2015. Retrieved 14 December 2015.
  9. ^ World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.

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