Saccharin

Saccharin^[1]^[2]
Names
	Preferred IUPAC name 1H-1λ6,2-Benzothiazole-1,1,3(2H)-trione
	Other names ortho-benzoic sulfimide; ortho sulphobenzimide;
Identifiers
CAS Number	81-07-2 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:32111 ;
ChEMBL	ChEMBL310671 ;
ChemSpider	4959 ;
ECHA InfoCard	100.001.202
E number	E954 (glazing agents, ...)
IUPHAR/BPS	5432;
KEGG	D01085 ;
PubChem CID	5143;
UNII	FST467XS7D ;
CompTox Dashboard (EPA)	DTXSID5021251 ;
	InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) Key: CVHZOJJKTDOEJC-UHFFFAOYSA-N ; InChI=1/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) Key: CVHZOJJKTDOEJC-UHFFFAOYAR;
	SMILES O=C2c1ccccc1S(=O)(=O)N2;
Properties
Chemical formula	C7H5NO3S
Molar mass	183.18 g·mol−1
Appearance	White crystalline solid
Density	0.828 g/cm3
Melting point	228.8 to 229.7 °C (443.8 to 445.5 °F; 501.9 to 502.8 K)
Solubility in water	1 g per 290 mL
Acidity (pKa)	1.6
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Saccharin, also called saccharine, benzosulfimide, or E954, or used in saccharin sodium or saccharin calcium forms, is a non-nutritive artificial sweetener.^[1]^[5] Saccharin is a sultam that is about 500 times sweeter than sucrose, but has a bitter or metallic aftertaste, especially at high concentrations.^[1] It is used to sweeten products, such as drinks, candies, baked goods, tobacco products, excipients, and for masking the bitter taste of some medicines.^[1]^[5] It appears as white crystals and is odorless.^[1]

^ ^a ^b ^c ^d ^e "Saccharin". PubChem, US National Library of Medicine. 13 June 2023. Retrieved 15 June 2023.
^ "Saccharin (CAS: 81-07-2)". Merck Millipore. 2023. Retrieved August 22, 2022.
^ NCERT Chemistry Part II Textbook for Class XII. Delhi: NCERT. 2021. p. 449. ISBN 81-7450-716-7.
^ Cite error: The named reference BellHigginson was invoked but never defined (see the help page).
^ ^a ^b "Saccharin". Drugs.com. 16 August 2022. Retrieved 15 June 2023.

[pubchem-1] "Saccharin". PubChem, US National Library of Medicine. 13 June 2023. Retrieved 15 June 2023.

[Merck_Millipore-2] "Saccharin (CAS: 81-07-2)". Merck Millipore. 2023. Retrieved August 22, 2022.

[3] NCERT Chemistry Part II Textbook for Class XII. Delhi: NCERT. 2021. p. 449. ISBN 81-7450-716-7.

[BellHigginson-4] Cite error: The named reference BellHigginson was invoked but never defined (see the help page).

[drugs-5] "Saccharin". Drugs.com. 16 August 2022. Retrieved 15 June 2023.

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Names


Preferred IUPAC name 1H-1λ⁶,2-Benzothiazole-1,1,3(2H)-trione
Other names ortho-benzoic sulfimide ortho sulphobenzimide ^[3]
Identifiers
CAS Number	81-07-2^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:32111^N
ChEMBL	ChEMBL310671^Y
ChemSpider	4959^Y
ECHA InfoCard	100.001.202
E number	E954 (glazing agents, ...)
IUPHAR/BPS	5432
KEGG	D01085^Y
PubChem CID	5143
UNII	FST467XS7D^Y
CompTox Dashboard (EPA)	DTXSID5021251
InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)^Y Key: CVHZOJJKTDOEJC-UHFFFAOYSA-N^Y InChI=1/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) Key: CVHZOJJKTDOEJC-UHFFFAOYAR
SMILES O=C2c1ccccc1S(=O)(=O)N2
Properties
Chemical formula	C₇H₅NO₃S
Molar mass	183.18 g·mol⁻¹
Appearance	White crystalline solid
Density	0.828 g/cm³
Melting point	228.8 to 229.7 °C (443.8 to 445.5 °F; 501.9 to 502.8 K)
Solubility in water	1 g per 290 mL
Acidity (pK_a)	1.6^[4]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references