San Marco Altarpiece

San Marco Altarpiece
Artist	Fra Angelico
Year	1438–1443
Medium	Tempera on wood
Dimensions	220 cm × 227 cm (87 in × 89 in)
Location	San Marco Museum, Florence, Italy

The San Marco Altarpiece (also known as Madonna and Saints) is a painting by the Italian early Renaissance painter Fra Angelico, housed in the San Marco Museum of Florence, Italy. It was commissioned by Cosimo de' Medici the Elder, and was completed sometime between 1438 and 1443.

In addition to the main panel depicting the enthroned Virgin and Child surrounded by Angels and Saints, there were nine predella panels accompanying it, narrating the legend of the patron saints, Saints Cosmas and Damian.^[1] Only the main panel actually remains to be seen in the Convent of San Marco, Florence, Italy, today, along with two side panels depicting saints which were purchased back for the museum as recently as 2007.

The San Marco Altarpiece is known as one of the best early Renaissance paintings for its employment of metaphor and perspective, trompe-l'œil, and the intertwining of Dominican religious themes and symbols with contemporary, political messages.