Selective estrogen receptor modulator | |
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Drug class | |
![]() Tamoxifen, a nonsteroidal triphenylethylene antiestrogen and a widely used drug in the treatment of breast cancer. | |
Class identifiers | |
Synonyms | SERM; Estrogen receptor agonist/antagonist; ERAA |
Use | Breast cancer, infertility, osteoporosis, vaginal atrophy, dyspareunia, contraception, male hypogonadism, gynecomastia, breast pain, others |
ATC code | G03XC |
Biological target | Estrogen receptor |
Legal status | |
In Wikidata |
Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonists/antagonists (ERAAs),[1][2] are a class of drugs that act on estrogen receptors (ER).[3] Compared to pure ER agonists-antagonists (e.g., full agonists and silent antagonists), SERMs' activity is more tissue-specific, allowing them to selectively inhibit or stimulate estrogen-like action in various tissues.
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