Back جسيم متعرف على الإشارة Arabic Signál rozpoznávající částice Czech Signalerkennungspartikel German Partícula de reconocimiento de señal Spanish ذره شناسایی سیگنال Persian Particule de reconnaissance du signal French Partícula de recoñecemento do sinal Galician Particella di riconoscimento del segnale Italian シグナル認識粒子 Japanese Partícula de reconhecimento de sinal (PRS) Portuguese
 | This article is missing information about overall structure (as context for "S domain" pics and for mechanism description); rough structure and function of binding proteins. (October 2021) |
| signal recognition particle 9kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP9 | ||||||
| NCBI gene | 6726 | ||||||
| HGNC | 11304 | ||||||
| OMIM | 600707 | ||||||
| RefSeq | NM_003133 | ||||||
| UniProt | P49458 | ||||||
| Other data | |||||||
| Locus | Chr. 1 q42.12 | ||||||
| |||||||
| signal recognition particle 14kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP14 | ||||||
| NCBI gene | 6727 | ||||||
| HGNC | 11299 | ||||||
| OMIM | 600708 | ||||||
| RefSeq | NM_003134 | ||||||
| UniProt | P37108 | ||||||
| Other data | |||||||
| Locus | Chr. 15 q22 | ||||||
| |||||||
| signal recognition particle 19kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP19 | ||||||
| NCBI gene | 6728 | ||||||
| HGNC | 11300 | ||||||
| OMIM | 182175 | ||||||
| RefSeq | NM_003135 | ||||||
| UniProt | P09132 | ||||||
| Other data | |||||||
| Locus | Chr. 5 q21-q22 | ||||||
| |||||||
| signal recognition particle 54kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP54 | ||||||
| NCBI gene | 6729 | ||||||
| HGNC | 11301 | ||||||
| OMIM | 604857 | ||||||
| RefSeq | NM_003136 | ||||||
| UniProt | P61011 | ||||||
| Other data | |||||||
| Locus | Chr. 14 q13.2 | ||||||
| |||||||
| signal recognition particle 68kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP68 | ||||||
| NCBI gene | 6730 | ||||||
| HGNC | 11302 | ||||||
| OMIM | 604858 | ||||||
| RefSeq | NM_014230 | ||||||
| UniProt | Q9UHB9 | ||||||
| Other data | |||||||
| Locus | Chr. 17 q25.1 | ||||||
| |||||||
| signal recognition particle 72kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP72 | ||||||
| NCBI gene | 6731 | ||||||
| HGNC | 11303 | ||||||
| OMIM | 602122 | ||||||
| RefSeq | NM_006947 | ||||||
| UniProt | O76094 | ||||||
| Other data | |||||||
| Locus | Chr. 4 q11 | ||||||
| |||||||
| Signal recognition particle protein | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | ffh | ||||||
| Alt. symbols | p48, Srp54 | ||||||
| UniProt | P0AGD7 | ||||||
| |||||||
The signal recognition particle (SRP) is an abundant, cytosolic, universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets specific proteins to the endoplasmic reticulum in eukaryotes and the plasma membrane in prokaryotes.[1]
- ^ Tisdale S, Pellizzoni L (2017-01-01). "Chapter 7 - RNA-Processing Dysfunction in Spinal Muscular Atrophy". In Sumner CJ, Paushkin S, KO CP (eds.). Spinal Muscular Atrophy. Academic Press. pp. 113–131. doi:10.1016/b978-0-12-803685-3.00007-0. ISBN 978-0-12-803685-3.
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