Thomas Cech

Thomas Cech
Cech in 2005
Born (1947-12-08) December 8, 1947 (age 77)
Chicago, Illinois, US
EducationGrinnell College (B.A., 1970)
University of California, Berkeley (Ph.D., 1975)
Known forRibozyme, Telomerase
AwardsPfizer Award in Enzyme Chemistry (1985)
Newcomb Cleveland Prize (1986)
NAS Award in Molecular Biology (1987)
Rosenstiel Award (1988)
Nobel Prize in Chemistry (1989)
National Medal of Science (1995)
Othmer Gold Medal (2007)
Scientific career
InstitutionsUniversity of Colorado, Howard Hughes Medical Institute
ThesisCharacterization of the most rapidly renaturing sequences in the main band DNA of the mouse (Mus musculus) (1975)
Doctoral advisorJohn E. Hearst

Thomas Robert Cech[a] (born 8 December 1947) is an American chemist who shared the 1989 Nobel Prize in Chemistry with Sidney Altman for their discovery of the catalytic properties of RNA.

Cech discovered that RNA could itself cut strands of RNA, suggesting that life might have started as RNA.[2] He found that RNA can not only transmit instructions, but can act as a catalyst to speed up the necessary reactions.[3]

He has also studied telomeres, and his lab discovered an enzyme, TERT (telomerase reverse transcriptase), which is part of the process of restoring telomeres after they are shortened during cell division.[4]

As president of Howard Hughes Medical Institute he has promoted science education, and he teaches an undergraduate chemistry course at the University of Colorado.

  1. ^ Source: Cech introducing himself at the beginning of various videos on YouTube.
  2. ^ The Nobel Prize in Chemistry 1989: Illustrated Presentation
  3. ^ Thomas Cech – Hyde Park Civilizace | Česká televize (in Czech), retrieved July 13, 2023
  4. ^ Telomeres, Telomerase, and Other Noncoding RNAs, Howard Hughes Medical Institute, July 13, 2010


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