Thomas Paine (1737–1809) was an English-American political activist, philosopher, political theorist, and revolutionary
Thomas Paine may also refer to:
- Thomas O. Paine (1921–1992), American scientist and NASA administrator
- Thomas Paine (privateer) (1632–1715), colonial American privateer
- John Kricfalusi, who took Thomas Paine as his pen name when writing for Film Threat and Wild Cartoon Kingdom
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