Thymol

Thymol
Names
	Preferred IUPAC name 5-Methyl-2-(propan-2-yl)phenol
	Systematic IUPAC name 5-Methyl-2-(propan-2-yl)benzenol
	Other names 2-Isopropyl-5-methylphenol, isopropyl-m-cresol, 1-methyl-3-hydroxy-4-isopropylbenzene, 3-methyl-6-isopropylphenol, 5-methyl-2-(1-methylethyl)phenol, 5-methyl-2-isopropyl-1-phenol, 5-methyl-2-isopropylphenol, 6-isopropyl-3-methylphenol, 6-isopropyl-m-cresol, Apiguard, NSC 11215, NSC 47821, NSC 49142, thyme camphor, m-thymol, and p-cymen-3-ol
Identifiers
CAS Number	89-83-8 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:27607 ;
ChEMBL	ChEMBL29411 ;
ChemSpider	21105998 ;
DrugBank	DB02513 ;
ECHA InfoCard	100.001.768
EC Number	201-944-8;
IUPHAR/BPS	2499;
KEGG	D01039 ;
PubChem CID	6989;
UNII	3J50XA376E ;
CompTox Dashboard (EPA)	DTXSID6034972 ;
	InChI InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 Key: MGSRCZKZVOBKFT-UHFFFAOYSA-N ; InChI=1/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 Key: MGSRCZKZVOBKFT-UHFFFAOYAS;
	SMILES CC(C)c1ccc(C)cc1O;
Properties
Chemical formula	C10H14O
Molar mass	150.221 g·mol−1
Density	0.96 g/cm3
Melting point	49 to 51 °C (120 to 124 °F; 322 to 324 K)
Boiling point	232 °C (450 °F; 505 K)
Solubility in water	0.9 g/L (20 °C)
Refractive index (nD)	1.5208
Pharmacology
ATCvet code	QP53AX22 (WHO)
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302, H314, H411
Precautionary statements	P260, P264, P270, P273, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P391, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Thymol (also known as 2-isopropyl-5-methylphenol, IPMP), C₁₀H₁₄O, is a natural monoterpenoid phenol derivative of p-Cymene, isomeric with carvacrol, found in oil of thyme, and extracted from Thymus vulgaris (common thyme), ajwain,^[4] and various other plants as a white crystalline substance of a pleasant aromatic odor and strong antiseptic properties. Thymol also provides the distinctive, strong flavor of the culinary herb thyme, also produced from T. vulgaris. Thymol is only slightly soluble in water at neutral pH, but it is extremely soluble in alcohols and other organic solvents. It is also soluble in strongly alkaline aqueous solutions due to deprotonation of the phenol. Its dissociation constant (pK_a) is 10.59±0.10.^[5] Thymol absorbs maximum UV radiation at 274 nm.^[6]

^ "Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 691. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
^ "Thymol". PubChem. Retrieved 1 April 2016.
^ Mndzhoyan, A. L. (1940). "Thymol from Thymus kotschyanus". Sbornik Trudov Armyanskogo Filial. Akad. Nauk. 1940: 25–28.
^ O'Connell, John (27 August 2019). The book of spice : from anise to zedoary. New York: Pegasus. ISBN 978-1681774459. OCLC 959875923.
^ CAS Registry: Data obtained from SciFinder^{[full citation needed]}
^ Norwitz, G.; Nataro, N.; Keliher, P. N. (1986). "Study of the Steam Distillation of Phenolic Compounds Using Ultraviolent Spectrometry". Anal. Chem. 58 (639–640): 641. doi:10.1021/ac00294a034.

[iupac2013-1] "Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 691. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.

[2] "Thymol". PubChem. Retrieved 1 April 2016.

[3] Mndzhoyan, A. L. (1940). "Thymol from Thymus kotschyanus". Sbornik Trudov Armyanskogo Filial. Akad. Nauk. 1940: 25–28.

[4] O'Connell, John (27 August 2019). The book of spice : from anise to zedoary. New York: Pegasus. ISBN 978-1681774459. OCLC 959875923.

[5] CAS Registry: Data obtained from SciFinder^{[full citation needed]}

[6] Norwitz, G.; Nataro, N.; Keliher, P. N. (1986). "Study of the Steam Distillation of Phenolic Compounds Using Ultraviolent Spectrometry". Anal. Chem. 58 (639–640): 641. doi:10.1021/ac00294a034.

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