U.S. Route 52 in Iowa

U.S. Highway 52
US 52 highlighted in red
Route information
Maintained by Iowa DOT
Length	173.722 mi[1] (279.578 km)
Existed	1935[2]–present
Major junctions
South end	US 52 / IL 64 at Savanna, Ill.
Major intersections	US 67 near Sabula US 61 / US 151 south of Dubuque US 20 west of Dubuque US 18 at Postville
North end	US 52 near Burr Oak
Location
Country	United States
State	Iowa
Counties	Jackson Dubuque Clayton Allamakee Winneshiek
Highway system
United States Numbered Highway System List Special Divided Iowa Primary Highway System Interstate US State Secondary Scenic
← Iowa 51 → Iowa 56

U.S. Highway 52 (US 52) is a 166-mile-long (267 km) United States Numbered Highway in northeast Iowa. The route begins at the Dale Gardner Veterans Memorial Bridge over the Mississippi River between Sabula and Savanna, Illinois. From Sabula, it heads north along the Mississippi towards Bellevue and Dubuque. At Dubuque, US 52 briefly shares an expressway with US 61 and US 151 before joining the Southwest Arterial, another expressway diverting traffic around the southern edge of Dubuque.

West of Dubuque, the route concurrently follows the US 20 expressway before joining Iowa Highway 136 (Iowa 136) in Dyersville. At Luxemburg, it continues north towards Guttenberg. It then heads northwest where it overlaps US 18 for 15 miles (24 km). At Calmar, US 52 turns to the north towards Decorah. US 52 crosses into Minnesota north of Burr Oak.

Despite its even number, US 52 is signed as a north–south route. According to the layout of the U.S. Highway System, even-numbered routes are generally signed as east–west routes.