U.S. Route 60 in Missouri

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U.S. Route 60
US 60 highlighted in red
Route information
Maintained by MoDOT
Length	341.248 mi[1] (549.185 km)
Existed	1926–present
Major junctions
West end	US 60 at Oklahoma state line in Seneca
Major intersections	I-49 / US 71 in Neosho US 160 in Springfield US 65 in Springfield US 63 in Cabool US 67 in Poplar Bluff Future I-57 / US 67 in Poplar Bluff I-55 / I-57 in Sikeston US 62 in Charleston
East end	US 60 / US 62 at Illinois state line east of Charleston
Location
Country	United States
State	Missouri
Counties	Newton, Barry, Lawrence, Christian, Greene, Webster, Wright, Texas, Howell, Shannon, Carter, Butler, Stoddard, New Madrid, Scott, Mississippi
Highway system
United States Numbered Highway System List Special Divided Missouri State Highway System Interstate US State Supplemental
← Route 59 → US 61

U.S. Route 60 (US 60) is a part of the United States Numbered Highway System that runs from Brenda, Arizona, east to Virginia Beach, Virginia. In the state of Missouri, US 60 is a main east–west highway that runs through the southern part of the state, from the Oklahoma border to the Illinois border.