Umifenovir

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Umifenovir

Clinical data
Trade names	Arbidol
Other names	AR-1I9514, Russian: Арбидол, Chinese: 阿比朵尔.[citation needed]
Pregnancy category	C
Routes of administration	By mouth (hard capsules, tablets)
ATC code	J05AX13 (WHO)
Legal status
Legal status	RU OTC[1] CN Rx-only[1] BY OTC[2]
Pharmacokinetic data
Bioavailability	40%
Metabolism	Hepatic, CYP3A4[3][4]
Elimination half-life	17–21 hours[3][4]
Excretion	40% excrete as unchanged umifenovir in feces (38.9%) and urine (0.12%)[5]
Identifiers
IUPAC name ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indole-3-carboxylate
CAS Number	131707-25-0 N
PubChem CID	131411
DrugBank	DB13609 Y
ChemSpider	116151 Y
UNII	93M09WW4RU
KEGG	D10558
ChEBI	CHEBI:134730
ChEMBL	ChEMBL1214598
PDB ligand	75U (PDBe, RCSB PDB)
CompTox Dashboard (EPA)	DTXSID60895015
ECHA InfoCard	100.247.800
Chemical and physical data
Formula	C22H25BrN2O3S
Molar mass	477.42 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCOC(=O)c1c(n(c2c1c(c(c(c2)Br)O)CN(C)C)C)CSc3ccccc3
InChI InChI=1S/C22H25BrN2O3S/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3/h6-11,26H,5,12-13H2,1-4H3 N Key:KCFYEAOKVJSACF-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Umifenovir, sold under the brand name Arbidol, is sold and used as an antiviral medication for influenza in Russia and China. The drug is manufactured by Pharmstandard (Russian: Фармстандарт). It is not approved by the U.S. Food and Drug Administration (FDA) for the treatment or prevention of influenza.^[6]