Weathering hypothesis

Arline Geronimus wrote about the weathering hypothesis the early 1990s to account for health disparities of newborn babies and birth mothers due to decades and generations of racism and social, economic, and political oppression. It is well documented that people of color and other marginalized communities have worse health outcomes than white people.[1] This is due to multiple stressors including prejudice, social alienation, institutional bias, political oppression, economic exclusion, and racial discrimination.[2] The weathering hypothesis proposes that the cumulative burden of these stressors as individuals age is "weathering", and the increased weathering experienced by minority groups compared to others can account for differences in health outcomes.[3] In recent years, social scientists investigated the biological plausibility of the weathering hypothesis in studies evaluating the physiological effects of social, environmental and political stressors among marginalized communities.[4] The weathering hypothesis is more widely accepted as a framework for explaining health disparities on the basis of differential exposure to racially based stressors.[5] Researchers have also identified patterns connecting weathering to biological phenomena associated with stress and aging, such as allostatic load, epigenetics, telomere shortening, and accelerated brain aging.[6][7][8][9]

  1. ^ Riley, Wayne J. (2012). "Health Disparities: Gaps in Access, Quality and Affordability of Medical Care". Transactions of the American Clinical and Climatological Association. 123: 167–174. ISSN 0065-7778. PMC 3540621. PMID 23303983.
  2. ^ Williams, David R.; Mohammed, Selina A. (2009). "Discrimination and racial disparities in health: evidence and needed research". Journal of Behavioral Medicine. 32 (1): 20–47. doi:10.1007/s10865-008-9185-0. ISSN 1573-3521. PMC 2821669. PMID 19030981.
  3. ^ Morello-Frosch, Rachel; Shenassa, Edmond D. (2008). "The Environmental "Riskscape" and Social Inequality: Implicationsfor Explaining Maternal and Child Health Disparities". Environmental Health Perspectives. 114 (8): 1150–1153. doi:10.1289/ehp.8930. ISSN 0091-6765. PMC 1551987. PMID 16882517.
  4. ^ Geronimus, Arline T.; Hicken, Margaret T.; Pearson, Jay A.; Seashols, Sarah J.; Brown, Kelly L.; Cruz, Tracey Dawson (2010). "Do US Black Women Experience Stress-Related Accelerated Biological Aging?". Human Nature. 21 (1): 19–38. doi:10.1007/s12110-010-9078-0. ISSN 1936-4776. PMC 2861506. PMID 20436780.
  5. ^ Keene, Danya E.; Geronimus, Arline T. (2011). "'Weathering' HOPE VI: The Importance of Evaluating the Population Health Impact of Public Housing Demolition and Displacement". Journal of Urban Health. 88 (3): 417–435. doi:10.1007/s11524-011-9582-5. ISSN 1099-3460. PMC 3126923. PMID 21607787.
  6. ^ Geronimus, Arline T. (2013). "Deep Integration: Letting the Epigenome Out of the Bottle Without Losing Sight of the Structural Origins of Population Health". American Journal of Public Health. 103 (S1): S56–S63. doi:10.2105/ajph.2013.301380. PMC 3786760. PMID 23927509.
  7. ^ Holzman, Claudia; Eyster, Janet; Kleyn, Mary; Messer, Lynne C.; Kaufman, Jay S.; Laraia, Barbara A.; O'Campo, Patricia; Burke, Jessica G.; Culhane, Jennifer; Elo, Irma T. (2009). "Maternal Weathering and Risk of Preterm Delivery". American Journal of Public Health. 99 (10): 1864–1871. doi:10.2105/AJPH.2008.151589. ISSN 0090-0036. PMC 2741514. PMID 19696383.
  8. ^ Riggan, Kirsten; Gilbert, Anna; Allyse, Megan (2020). "Acknowledging and Addressing Allostatic Load in Pregnancy Care". Journal of Racial and Ethnic Health Disparities. 8 (1): 69–79. doi:10.1007/s40615-020-00757-z. ISSN 2197-3792. PMC 7647942. PMID 32383045.
  9. ^ McDonough, I. M. (2017). Beta-amyloid and cortical thickness reveal racial disparities in preclinical Alzheimer's disease. NeuroImage: Clinical, 16, 659-667.doi:10.1016/j.nicl.2017.09.014

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