William Bainbridge (1774–1833) was a commodore in the U.S. Navy.
William Bainbridge may also refer to:
- Bill Bainbridge (1922–1966), English footballer
- William G. Bainbridge (1925–2008), U.S. Army officer
- William Sims Bainbridge (born 1940), American sociologist
- William Seaman Bainbridge (1870–1947), American surgeon and gynecologist
- William Bainbridge (lawyer) (1811–1869) British lawyer and writer associated with Newcastle upon Tyne
- William Bainbridge (MP) (died 1583), MP for Derby
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