Oxygen-18

Oxygen-18, 18O
General
Symbol18O
Namesoxygen-18, 18O, O-18,
Ω, Heavy oxygen
Protons (Z)8
Neutrons (N)10
Nuclide data
Natural abundance0.2%
Half-life (t1/2)stable
Isotope mass17.9991610 Da
Spin0
Isotopes of oxygen
Complete table of nuclides

Oxygen-18 (18
O
, Ω[1]) is a natural, stable isotope of oxygen and one of the environmental isotopes.

18
O
is an important precursor for the production of fluorodeoxyglucose (FDG) used in positron emission tomography (PET). Generally, in the radiopharmaceutical industry, enriched water (H
2
Ω) is bombarded with hydrogen ions in either a cyclotron or linear accelerator, producing fluorine-18. This is then synthesized into FDG and injected into a patient. It can also be used to make an extremely heavy version of water when combined with tritium (hydrogen-3): 3
H
2
18
O
or T
2
Ω. This compound has a density almost 30% greater than that of natural water.[2]

The accurate measurements of 18
O
rely on proper procedures of analysis, sample preparation and storage.[3]

  1. ^ Capilla, José E.; Arevalo, Javier Rodriguez; Castaño, Silvino Castaño; Teijeiro, María Fé Díaz; del Moral, Rut Sanchez; Diaz, Javier Heredia (September 19, 2012). "Mapping Oxygen-18 in Meteoric Precipitation over Peninsular Spain using Geostatistical Tools" (PDF). cedex.es. Valencia, Spain: Ninth Conference on Geostatistics for Environmental Applications. Retrieved May 8, 2017.
  2. ^ Pauling, Linus (1988). "12-7. Heavy Water". General Chemistry (3rd ed.). Dover. p. 438. ISBN 978-0-486-65622-9.
  3. ^ Tsang, Man-Yin; Yao, Weiqi; Tse, Kevin (2020). Kim, Il-Nam (ed.). "Oxidized silver cups can skew oxygen isotope results of small samples". Experimental Results. 1: e12. doi:10.1017/exp.2020.15. ISSN 2516-712X.

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