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Anhedonia

For other uses, see Anhedonia (disambiguation).

Anhedonia
Melancholia, by Tadeusz Pruszkowski
Pronunciation
SpecialtyPsychiatry
SymptomsReduced motivation and ability to experience pleasure, particularly from previously enjoyable activities

Anhedonia is a diverse array of deficits in hedonic function, including reduced motivation or ability to experience pleasure.[1] While earlier definitions emphasized the inability to experience pleasure, anhedonia is currently used by researchers to refer to reduced motivation, reduced anticipatory pleasure (wanting), reduced consummatory pleasure (liking), and deficits in reinforcement learning.[2][3][4] In the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), anhedonia is a component of depressive disorders, substance-related disorders, psychotic disorders, and personality disorders, where it is defined by either a reduced ability to experience pleasure, or a diminished interest in engaging in previously pleasurable activities.[5][6] While the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) does not explicitly mention anhedonia, the depressive symptom analogous to anhedonia as described in the DSM-5 is a loss of interest or pleasure.[3]

  1. ^ Rizvi SJ, Pizzagalli DA, Sproule BA, Kennedy SH (June 2016). "Assessing anhedonia in depression: Potentials and pitfalls". Neuroscience and Biobehavioral Reviews. 65: 21–35. doi:10.1016/j.neubiorev.2016.03.004. PMC 4856554. PMID 26959336.
  2. ^ Shankman S, Katz A, DeLizza A, Sarapas C, Gorka S, Campbell M (2014). "The Different Facets of Anhedonia and Their Associations with Different Psychopathologies". In Ritsner M (ed.). Anhedonia : a comprehensive handbook. Dordrecht: Springer Netherlands. p. 3. ISBN 978-94-017-8590-7. However, there are two components to the positive affect experienced in rewarding situations - anticipatory positive affect (APA) and cunsummatory positive affect (CPA)...Berridge and Robinson [2] describe these constructs as 'wanting' and 'liking', respectively.
  3. ^ a b Der-Avakian A, Markou A (January 2012). "The neurobiology of anhedonia and other reward-related deficits". Trends in Neurosciences. 35 (1): 68–77. doi:10.1016/j.tins.2011.11.005. PMC 3253139. PMID 22177980.
  4. ^ Treadway MT, Zald DH (January 2011). "Reconsidering anhedonia in depression: lessons from translational neuroscience". Neuroscience and Biobehavioral Reviews. 35 (3): 537–55. doi:10.1016/j.neubiorev.2010.06.006. PMC 3005986. PMID 20603146.
  5. ^ Rømer Thomsen K, Whybrow PC, Kringelbach ML (2015). "Reconceptualizing anhedonia: novel perspectives on balancing the pleasure networks in the human brain". Frontiers in Behavioral Neuroscience. 9: 49. doi:10.3389/fnbeh.2015.00049. PMC 4356228. PMID 25814941.
  6. ^ American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders : DSM-5 (5th ed.). Washington, D.C.: American Psychiatric Association. pp. 126, 202, 259, 350, 569, 582, 598, 603, 793, 800, 806, 842. ISBN 978-0-89042-554-1.

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