Salamander

Salamanders Temporal range: Late Jurassic – Present,[1] 160–0 Ma PreꞒ Ꞓ O S D C P T J K Pg N
Spotted salamander, Ambystoma maculatum
Scientific classification
Domain:	Eukaryota
Kingdom:	Animalia
Phylum:	Chordata
Class:	Amphibia
Clade:	Caudata
Order:	Urodela Duméril, 1806
Suborders
Cryptobranchoidea Salamandroidea
Native distribution of salamanders (in green)

Salamanders are a group of amphibians typically characterized by their lizard-like appearance, with slender bodies, blunt snouts, short limbs projecting at right angles to the body, and the presence of a tail in both larvae and adults. All ten extant salamander families are grouped together under the order Urodela from the group Caudata.^[2] Salamander diversity is highest in eastern North America, especially in the Appalachian Mountains; most species are found in the Holarctic realm, with some species present in the Neotropical realm.

Salamanders never have more than four toes on their front legs and five on their rear legs,^[3] but some species have fewer digits and others lack hind limbs. Their permeable skin usually makes them reliant on habitats in or near water or other cool, damp places. Some salamander species are fully aquatic throughout their lives, some take to the water intermittently, and others are entirely terrestrial as adults.

This group of amphibians is capable of regenerating lost limbs as well as other damaged parts of their bodies. Researchers hope to reverse engineer the regenerative processes for potential human medical applications, such as brain and spinal cord injury treatment or preventing harmful scarring during heart surgery recovery.^[4] The remarkable ability of salamanders to regenerate is not just limited to limbs but extends to vital organs such as the heart, jaw, and parts of the spinal cord, showing their uniqueness compared to different types of vertebrates. ⁤⁤This ability is most remarkable for occurring without any type of scarring. ⁤⁤This has made salamanders an invaluable model organism in scientific research aimed at understanding and achieving regenerative processes for medical advancements in human and animal biology.^[5]

Members of the family Salamandridae are mostly known as newts and lack the costal grooves along the sides of their bodies typical of other groups. The skin of some species contains the powerful poison tetrodotoxin; these salamanders tend to be slow-moving and have bright warning coloration to advertise their toxicity. Salamanders typically lay eggs in water and have aquatic larvae, but great variation occurs in their lifecycles. Some species in harsh environments reproduce while still in the larval state.