Sarin

Sarin[1]
S-Sarin
Names
Pronunciation /ˈsɑːrɪn/
Preferred IUPAC name
Propan-2-yl methylphosphonofluoridate
Other names
(RS)-O-Isopropyl methylphosphonofluoridate; IMPF;
GB;[2]
2-(Fluoro-methylphosphoryl)oxypropane;
Phosphonofluoridic acid, P-methyl-, 1-methylethyl ester
EA-1208
TL-1618
T-144
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
UNII
  • InChI=1S/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3 checkY
    Key: DYAHQFWOVKZOOW-UHFFFAOYSA-N checkY
  • InChI=1/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3
  • InChI=1/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3
    Key: DYAHQFWOVKZOOW-UHFFFAOYAY
  • FP(=O)(OC(C)C)C
Properties
C4H10FO2P
Molar mass 140.094 g·mol−1
Appearance Clear colourless liquid, brownish if impure
Odor Odourless in pure form. Impure sarin can smell like mustard or burned rubber.
Density 1.0887 g/cm3 (25 °C)
1.102 g/cm3 (20 °C)
Melting point −56 °C (−69 °F; 217 K)
Boiling point 158 °C (316 °F; 431 K)
Miscible
log P 0.30
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Extremely lethal cholinergic agent.
GHS labelling:
GHS06: Toxic
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 4: Very short exposure could cause death or major residual injury. E.g. VX gasFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability 1: Normally stable, but can become unstable at elevated temperatures and pressures. E.g. calciumSpecial hazards (white): no code
4
1
1
0.00003 mg/m3 (TWA), 0.0001 mg/m3 (STEL)
Lethal dose or concentration (LD, LC):
39 μg/kg (intravenous, rat)[3]
NIOSH (US health exposure limits):
IDLH (Immediate danger)
0.1 mg/m3
Safety data sheet (SDS) Lethal Nerve Agent Sarin (GB)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Sarin (NATO designation GB [short for G-series, "B"]) is an extremely toxic organophosphorus compound.[4] A colourless, odourless liquid, it is used as a chemical weapon due to its extreme potency as a nerve agent. Exposure can be lethal even at very low concentrations, where death can occur within one to ten minutes after direct inhalation of a lethal dose,[5][6] due to suffocation from respiratory paralysis, unless antidotes are quickly administered.[4] People who absorb a non-lethal dose and do not receive immediate medical treatment may suffer permanent neurological damage.[citation needed]

Sarin is widely considered a weapon of mass destruction. Production and stockpiling of sarin was outlawed as of April 1997 by the Chemical Weapons Convention of 1993, and it is classified as a Schedule 1 substance.

  1. ^ "Material Safety Data Sheet – Lethal Nerve Agent Sarin (GB)". 103d Congress, 2d Session. United States Senate. May 25, 1994. Retrieved November 6, 2004.
  2. ^ "Sarin". National Institute of Standards and Technology. Retrieved March 27, 2011.
  3. ^ "Substance Name: Sarin". ChemIDplus. U.S. National Library of Medicine, National Institutes of Health. Retrieved January 19, 2020.
  4. ^ a b Sarin (GB). Emergency Response Safety and Health Database. National Institute for Occupational Safety and Health. Accessed April 20, 2009.
  5. ^ Anderson K (September 17, 2013). A Poisonous Affair: America, Iraq, and the Gassing of Halabja review of A Poisonous Affair: America, Iraq, and the Gassing of Halabja by Joost R. Hiltermann (Cambridge UP 2007). Lawfare: Hard National Security Choices (Report). Retrieved December 30, 2015. ... death can occur within one minute of direct inhalation as the lung muscles are paralyzed.
  6. ^ Smith M (August 26, 2002). "Saddam to be target of Britain's 'E-bomb'". The Daily Telegraph. p. A18. Retrieved December 30, 2015. The nerve agents sarin and VX. Colourless and tasteless, they cause death by respiratory arrest in one to 15 minutes.

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