Nuclear transfer

Nuclear transfer is a form of cloning. The step involves removing the DNA from an oocyte (unfertilised egg), and injecting the nucleus which contains the DNA to be cloned. In rare instances, the newly constructed cell will divide normally, replicating the new DNA while remaining in a pluripotent state. If the cloned cells are placed in the uterus of a female mammal, a cloned organism develops to term in rare instances. This is how Dolly the Sheep and many other species were cloned. Cows are commonly cloned to select those that have the best milk production. On 24 January 2018, two monkey clones were reported to have been created with the technique for the first time.^[1]^[2]^[3]

Despite this, the low efficiency of the technique has prompted some researchers, notably Ian Wilmut, creator of Dolly the cloned sheep, to abandon it.^[4]

^ Liu, Zhen; et al. (24 January 2018). "Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer". Cell. 172 (4): 881–887.e7. doi:10.1016/j.cell.2018.01.020. PMID 29395327.
^ Briggs, Helen (24 January 2018). "First monkey clones created in Chinese laboratory". BBC News. Retrieved 24 January 2018.
^ "Scientists Successfully Clone Monkeys; Are Humans Up Next?". The New York Times. Associated Press. 24 January 2018. Retrieved 24 January 2018.
^ Roger Highfield Dolly creator Prof Ian Wilmut shuns cloning. The Telegraph. 16 November 2007

[CELL-20180124-1] Liu, Zhen; et al. (24 January 2018). "Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer". Cell. 172 (4): 881–887.e7. doi:10.1016/j.cell.2018.01.020. PMID 29395327.

[BBC-20180124-2] Briggs, Helen (24 January 2018). "First monkey clones created in Chinese laboratory". BBC News. Retrieved 24 January 2018.

[NYT-20180124-3] "Scientists Successfully Clone Monkeys; Are Humans Up Next?". The New York Times. Associated Press. 24 January 2018. Retrieved 24 January 2018.

[4] Roger Highfield Dolly creator Prof Ian Wilmut shuns cloning. The Telegraph. 16 November 2007

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