Interstate 81 in Virginia

Interstate 81
I-81 highlighted in red
Route information
Maintained by VDOT
Length	324.92 mi[1] (522.91 km)
NHS	Entire route
Major junctions
South end	I-81 at Tennessee border in Bristol
Major intersections	I-381 in Bristol US 21 / US 52 in Wytheville I-77 near Wytheville US 460 in Christiansburg Future I-73 / I-581 / US 220 near Roanoke US 60 in Lexington I-64 from Lexington to Staunton US 250 near Staunton I-66 near Front Royal US 17 / US 50 / US 522 in Winchester
North end	I-81 at West Virginia border near Winchester
Location
Country	United States
State	Virginia
Counties	City of Bristol, Washington, Smyth, Wythe, Pulaski, Montgomery, Roanoke, City of Salem, City of Roanoke, Botetourt, Rockbridge, Augusta, Rockingham, City of Harrisonburg, Shenandoah, Warren, Frederick
Highway system
Interstate Highway System Main Auxiliary Suffixed Business Future Virginia Routes Interstate US Primary Secondary Byways History HOT lanes
← SR 80 → SR 82

Interstate 81 (I-81) is an 855.02-mile-long (1,376.02 km) Interstate Highway. In the US state of Virginia, I-81 runs for 324.92 miles (522.91 km), making the portion in Virginia longer than any other state's portion of the route. It is also the longest Interstate Highway within the borders of Virginia. It stretches from the Tennessee state line near Bristol to the West Virginia state line near Winchester. It enters Virginia from Bristol, Tennessee, and leaves Virginia into Berkeley County, West Virginia. The route passes through the cities of Bristol, Roanoke, Lexington, Staunton, and Harrisonburg.