Back Vacuna de Moderna contra la COVID-19 AN لقاح موديرنا Arabic Vaksin COVID-19 Moderna BJN মডার্না কোভিড-১৯ টিকা Bengali/Bangla Moderna (vakcina) BS Moderna COVID-19 vaccine BXR Vaccí de Moderna contra la COVID-19 Catalan Vakcína Moderna proti covidu-19 Czech Elasomeran German Εμβόλιο COVID-19 της Moderna Greek

Moderna COVID-19 vaccine

"Moderna vaccine" redirects here. For other Moderna vaccination topics, see Moderna.

Moderna COVID-19 vaccine
Vials of the Moderna COVID-19 vaccine
Vaccine description
TargetSARS-CoV-2
Vaccine typemRNA
Clinical data
Trade namesSpikevax[1][2]
Other namesmRNA-1273, CX-024414, COVID-19 mRNA Vaccine Moderna, TAK-919, Moderna COVID‑19 Vaccine, COVID‑19 Vaccine Moderna, COVID-19 Vaccine Moderna Intramuscular Injection,[3] elasomeran,[4][5] COVID-19 Vaccine (mRNA),[6] davesomeran,[4] imelasomeran,[4] andusomeran,[4] CX-034476, CX-038839
AHFS/Drugs.comMonograph
MedlinePlusa621002
License data
Pregnancy
category
Routes of
administration		Intramuscular
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem SID
DrugBank
UNII
KEGG
ChEMBL
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The Moderna COVID‑19 vaccine, sold under the brand name Spikevax, is a COVID-19 vaccine developed by the American company Moderna, the United States National Institute of Allergy and Infectious Diseases (NIAID), and the Biomedical Advanced Research and Development Authority (BARDA). Depending on the jurisdiction, it is authorized for use in humans aged six months,[47] twelve years, or eighteen years and older. It provides protection against COVID-19, which is caused by infection by the SARS-CoV-2 virus.[41][2][21][14] It is designed to be administered in two or three 0.5-mL doses given by intramuscular injection at an interval of at least 28 days apart.[32][48][49][50]

It is an mRNA vaccine composed of nucleoside-modified mRNA (modRNA) encoding a spike protein of SARS-CoV-2, which is encapsulated in lipid nanoparticles.[51]

It is authorized for use at some level in many countries.[52][53][54][55]

In August and September 2022, bivalent versions of the vaccine (Moderna COVID-19 Vaccine, Bivalent) containing elasomeran/elasomeran 0-omicron (Spikevax Bivalent Zero/Omicron)[56] were authorized for use as booster doses in individuals aged 18 years of age or older in the United Kingdom,[57][58] Switzerland,[59] Australia,[60] Canada,[61][62] the European Union,[2] and the United States.[63][64] The second component of the version of the bivalent vaccine used in the United States (mRNA-1273.222[65]) is based on the Omicron BA.4/BA.5 variant,[63] while the second component of the bivalent vaccine version used in other countries (mRNA-1273.214) is based on the Omicron BA.1 variant.[2][56][58][57][62]

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  2. ^ a b c d e "Spikevax (previously COVID-19 Vaccine Moderna) EPAR". European Medicines Agency (EMA). 4 January 2021. Archived from the original on 1 February 2022. Retrieved 31 January 2022.
  3. ^ "Takeda Announces Approval of Moderna's COVID-19 Vaccine in Japan" (Press release). Takeda. 21 May 2021. Archived from the original on 23 December 2021. Retrieved 29 May 2021.
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  6. ^ "Updates to the Prescribing Medicines in Pregnancy database". Therapeutic Goods Administration (TGA). 21 December 2022. Retrieved 2 January 2023.
  7. ^ a b "Spikevax". Therapeutic Goods Administration (TGA). 9 August 2021. Archived from the original on 28 August 2021. Retrieved 28 August 2021.
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  9. ^ "Updates to the Prescribing Medicines in Pregnancy database". Therapeutic Goods Administration (TGA). 12 May 2022. Archived from the original on 3 April 2022. Retrieved 13 May 2022.
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  11. ^ "COVID-19 vaccine: Spikevax (elasomeran)". Therapeutic Goods Administration (TGA). 21 June 2022. Retrieved 9 October 2023.
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  14. ^ a b Cite error: The named reference TGA provisional approval 2 was invoked but never defined (see the help page).
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  33. ^ "Moderna COVID-19 Vaccine Standing Orders for Administering Vaccine to Persons 12 Years Through 17 Years of Age" (PDF). Centers for Disease Control and Prevention (CDC). 11 July 2022. Archived (PDF) from the original on 16 July 2022. Retrieved 14 July 2022. Public Domain This article incorporates text from this source, which is in the public domain.
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  41. ^ a b "Moderna COVID-19 Vaccine- cx-024414 injection, suspension". DailyMed. 17 June 2022. Archived from the original on 18 June 2022. Retrieved 17 June 2022.
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  44. ^ Cite error: The named reference Spikevax EC Union Register was invoked but never defined (see the help page).
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  46. ^ "Spikevax Product information". Union Register of medicinal products. Retrieved 3 March 2023.
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