2022 Missouri marijuana legalization initiative

Constitutional Amendment 3
Marijuana Legalization Initiative
Results
Yes 70–80% 60–70% 50–60%	No 70–80% 60–70% 50–60%
	Source: Missouri Secretary of State

2022 Missouri Constitutional Amendment 3, also known as the Marijuana Legalization Initiative, was a ballot measure to amend the Constitution of Missouri to legalize cannabis at the state level in Missouri. The measure was on the November 7, 2022, general ballot and was approved by voters with a margin of 53–47 percent.